ComfyUI Desktop Installation Fails on NVIDIA RTX 5090 After Windows Reinstallation

A user on Reddit's r/comfyui community has reported an inability to reinstall the desktop version of ComfyUI following a fresh Windows operating system installation. The user, who previously had ComfyUI and WAN 2.2 workflows running successfully for a month, states that clicking the setup executable now yields no response—no black box, no error messages, just a complete lack of activity. This issue is reported on a system equipped with an NVIDIA RTX 5090 GPU, indicating a high-performance hardware configuration.

While this appears to be an isolated user report, the nature of the problem—a silent installer failure—suggests potential underlying system dependency conflicts, driver issues, or specific interactions with the new Windows environment on a cutting-edge GPU. The user's preference for the desktop version over the portable one highlights the importance of robust and straightforward installation processes for production environments. Troubleshooting in such cases typically involves verifying system prerequisites, driver integrity, and potential conflicts with antivirus software or Windows security settings.

For studios and buyers, this underscores the critical need for stable and predictable installation and update procedures for AI video tools. While individual user issues are common, any reported instability, especially on high-end hardware, warrants attention. Production pipelines rely on consistent tool functionality, and unexpected installation hurdles can lead to significant downtime and project delays. Ensuring that core AI tools like ComfyUI maintain broad compatibility and robust installers across various system configurations, including the latest GPUs, is paramount for maintaining operational efficiency and minimizing technical friction in AI-driven creative workflows.